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目的 :探讨脑利钠肽 (BNP)血浆浓度与脑血管痉挛 (CVS)的关系。方法 :32例自发性蛛网膜下腔出血患者与1 5例健康者对照 ,分别在不同时段测定BNP浓度 ,并进行比较分析。结果 :与对照组比较 ,SAH病人BNP水平显著升高(P <0 0 5) ,症状性CVS病人在不同时段BNP水平显著递增 (P <0 0 1 )。结论 :在SAH患者出现CVS最初 2周内血BNP浓度明显升高 ,可作为预测CVS的一个重要指标
Objective: To investigate the relationship between brain natriuretic peptide (BNP) plasma concentration and cerebral vasospasm (CVS). Methods: Thirty-two patients with spontaneous subarachnoid hemorrhage were compared with 15 healthy controls. BNP levels were measured at different time points and compared. Results: Compared with the control group, the level of BNP in patients with SAH was significantly increased (P <0.05). The levels of BNP in patients with symptomatic CVS were significantly increased at different time points (P <0.01). CONCLUSIONS: Serum BNP levels are significantly elevated in the first 2 weeks of CVS in patients with SAH and can be used as an important predictor of CVS