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目的:检测多囊卵巢综合征(PCOS)患者血清GnSAF水平,探讨其在PCOS发病的意义。方法 :选取61名PCOS患者及64名对照者,计算体重指数(BMI)及腰臀比(WHR),采用电化学发光法测定生殖性激素,包括卵泡刺激素(FSH)、黄体生成素(LH)、雌二醇(E2)、催乳素(PRL)、睾酮(T),采用酶联免疫吸附法测定血清GnSAF水平。结果:两组间年龄及WHR均无统计学意义;BMI比较差异有统计学意义;PCOS组GnSAF血清浓度高于对照组,但差异没有统计学意义;除E2与GnSAF呈负相关,有统计学意义外,其余各指标与GnSAF均无相关性。结论:PCOS患者血清GnSAF水平升高,可能与PCOS发病、卵泡发育障碍有关。
Objective: To detect the level of serum GnSAF in patients with polycystic ovary syndrome (PCOS) and to explore its significance in the pathogenesis of PCOS. Methods: 61 PCOS patients and 64 controls were selected to calculate the body mass index (BMI) and waist-to-hip ratio (WHR). The levels of reproductive hormones, including FSH, LH, , Estradiol (E2), prolactin (PRL) and testosterone (T). Serum GnSAF levels were measured by enzyme-linked immunosorbent assay. Results: There was no significant difference in age and WHR between the two groups. There was significant difference in BMI between the two groups. The serum concentration of GnSAF in PCOS group was higher than that in control group, but the difference was not statistically significant. Significance, the rest of the indicators and GnSAF no correlation. Conclusion: Serum GnSAF levels in PCOS patients may be related to the pathogenesis of PCOS and follicular dysplasia.