论文部分内容阅读
目的探讨正常妊娠妇女、妊娠期糖尿病(GDM)患者羊水C肽(amnioticfluidC-peptide,AFCP)与胰岛素水平的变化,了解其与新生儿并发症的关系。方法用放射免疫法测定正常妊娠组(Ⅰ组)60例,GDM患者(Ⅱ组)60例的羊水C肽和胰岛素水平。结果两组羊水C肽水平有显著性差异(P<0.01),Ⅱ组胰岛素水平孕30～34周时明显高于Ⅰ组(P<0.05),生产时明显低于Ⅰ组(P<0.05)。结论羊水C肽值可更直接反应胎儿胰腺β细胞分泌功能,为临床预防新生儿并发症提供数据支持。
Objective To investigate the changes of amniotic fluid C-peptide (amniotic fluid C-peptide, AFCP) and insulin levels in normal pregnant women and gestational diabetes mellitus (GDM) patients and to investigate their relationship with neonatal complications. Methods The levels of amniotic fluid C-peptide and insulin in 60 pregnant women (group Ⅰ) and 60 women with GDM (group Ⅱ) were measured by radioimmunoassay. Results The level of amniotic fluid C peptide was significantly different between the two groups (P <0.01). The level of insulin in group Ⅱ was significantly higher than that of group Ⅰ (P <0.05) at 30-34th week of pregnancy and significantly lower than that of group Ⅰ (P <0.05) . Conclusion Amniotic fluid C peptide value can more directly reflect the pancreatic β-cell secretion, providing clinical data for the prevention of neonatal complications.