Temporal Expression of Notch in Preterm Rat Lungs Exposed to Hyperoxia

• 作 者: 汪鸿 常立文 李文斌
• 机 构: DepartmentofPediatrics
• 出 处: 华中科技大学学报(医学英德文版)
• 发表日期: 2005年2期
• 关键词: 过氧化损伤 肺损伤 小鼠 动物实验 基因表达 Notch hyperoxia lung injury preterm transdifferentiat

To explore the mechanism of Notch in hyperoxia-induced preterm rat lung injury, 2days-old preterm SD rats were randomized into control and hyperoxia group (FiO2 ≥0.85). On day 1, 7, 14 and 21, 8 rat pups of each time point were used to assess histopatholo