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目的了解正常人及癫痫病人在不同生理状态下的脑电图的信息传输量的规律性 ,比较在不同条件下信息传输的差异。方法引用一种称为“信息传输”的理论来计算局灶性癫痫患者脑电的皮层信息传输序列 ,并计算该序列的复杂度 ,用复杂度来描述信息传输序列的信息含量。比较了正常人和局灶性癫痫病患者以及患者在诱发癫痫发作的不同时期的大脑皮层信息传输。结果发现局灶性癫痫病人的大脑皮层信息传输有非常特殊的现象。正常人各导联间的信息传输量趋于随机 ,未发现特别规律 ;而局灶性癫痫病人痫性导联与其它导联的皮层信息传输量在癫痫发作前 37s有所增加 (P <0 .0 5) ;在患者病情发作时期 ,痫性导联之间的信息传输量有明显增加 (P <0 .0 1 ) ,同时 ,该信息传输量也比正常人有显著增大 (P <0 .0 1 ) ;相反 ,非痫性导联之间的信息传输量有显著降低。结论认为这个方法在研究和理解人脑功能时可能是一个有潜力的方法 ,可能用于预报癫痫发作 ,是研究和诊断局灶性癫痫的一个新途径
Objective To understand the regularity of EEG transmission in normal and epileptic patients under different physiological conditions and to compare the differences in information transmission under different conditions. The method refers to a theory called “information transmission” to calculate the cortical information transmission sequence of electroencephalogram in patients with focal epilepsy, and calculates the complexity of the sequence, and uses the complexity to describe the information content of the information transmission sequence. Comparison of normal and focal epilepsy patients and patients in different stages of epilepsy induced cerebral cortex information transmission. The results found that patients with focal epilepsy cerebral cortex information transmission has a very special phenomenon. The normal transmission of information between the lead tends to be random, no special law was found; and epileptic seizures in patients with focal epileptic lead and other leads of the cortex information transmission increased 37s before seizure (P <0 .0 5). During the onset of the disease, the amount of information transmitted between the epileptic leads was significantly increased (P <0.01) and the amount of information transferred was also significantly increased (P < 0 .0 1); Conversely, there was a significant decrease in the amount of information transmitted between non-epileptic leads. The conclusion is that this method may be a potential method to study and understand human brain function, which may be used to predict seizures. It is a new way to study and diagnose focal epilepsy