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目的探究与分析头孢克洛和头孢克肟治疗小儿急性细菌性肠炎的临床疗效,旨在找出最佳治疗方式。方法选取我院自2012年5月至2013年5月收治的小儿急性细菌性肠炎60例,采取随机数字表法分为对照组与试验组。对照组患儿给予头孢克洛治疗,试验组患者给予头孢克肟治疗,观察并比较两组患儿在不同治疗方案下的临床疗效及不良反应。结果试验组患儿显效例数较对照组患儿显著增多,P<0.05,具有统计学意义;两组患儿有效例数无统计学意义(P>0.05);试验组患儿总有效例数较对照组多,P<0.05,具有统计学意义。两组患儿均未出现皮疹、恶心、呕吐等任何不良反应(P>0.05),无明显差异。结论经头孢克肟治疗小儿急性细菌性肠炎的临床效果较为突出,不良反应较少,具有一定的安全性,为患儿及其家属减少了经济负担,值得推广于临床实践中。
Objective To explore and analyze the clinical efficacy of cefaclor and cefixime in the treatment of acute bacterial enteritis in children and to find the best treatment. Methods Sixty children with acute bacterial enteritis in our hospital from May 2012 to May 2013 were selected and randomly divided into control group and experimental group. The control group was treated with cefaclor. The patients in the test group were given cefixime. The clinical efficacy and adverse reactions of the two groups were observed and compared under different treatment regimens. Results The number of effective cases in the experimental group was significantly higher than that in the control group (P <0.05), and there was no significant difference between the two groups (P> 0.05). The total number of effective cases in the experimental group More than the control group, P <0.05, with statistical significance. No adverse reactions such as rash, nausea and vomiting occurred in both groups (P> 0.05). There was no significant difference between the two groups. Conclusion The clinical effect of cefixime in the treatment of acute bacterial enteritis in children is prominent, with fewer adverse reactions, with a certain degree of safety, reducing the financial burden on children and their families, and is worth popularizing in clinical practice.