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目的通过分析T2DM患者踝肱指数(ABI)、微量白蛋白尿(MAU)与糖尿病心脑血管疾病的关系,比较两者在预测T2DM患者心脑血管疾病中的作用。方法回顾性分析531例T2DM患者的一般情况、生化指标、ABI、MAU以及心脑血管并发症的患病情况。结果 T2DM患者伴有心脑血管疾病者204例(38.4%)。ABI和MAU异常组较正常组年龄大、病程长、SBP和2hPG高,合并心脑血管疾病多。进一步按年龄和病程分组比较发现,≤60岁、病程≤15年时,ABI异常患者合并心脑血管并发症的比例不仅高于同年龄、同病程的ABI正常组,而且高于相应的MAU异常组(P<0.05)。结论 ABI和MAU异常同为T2DM患者心脑血管疾病的危险因素,但对于年龄小且病程短的患者,ABI对心脑血管疾病预测作用优于MAU。
Objective To analyze the relationship between ankle brachial index (ABI) and microalbuminuria (MAU) and diabetic cardiovascular and cerebrovascular diseases in patients with T2DM, and to compare their roles in the prediction of cardiovascular and cerebrovascular diseases in patients with T2DM. Methods A retrospective analysis of 531 cases of T2DM patients with general conditions, biochemical indicators, ABI, MAU and cardiovascular disease complications. Results 204 patients (38.4%) with T2DM were accompanied by cardiovascular and cerebrovascular diseases. ABI and MAU abnormal group older than the normal group, longer duration, SBP and 2hPG high, with more cardiovascular and cerebrovascular diseases. Further group by age and duration of disease found that ≤ 60 years of age, duration of ≤ 15 years, ABI abnormalities in patients with cardiovascular and cerebrovascular complications not only higher than the same age group, same duration of ABI normal group, and higher than the corresponding MAU abnormalities Group (P <0.05). Conclusions Abnormalities of ABI and MAU are risk factors of cardiovascular and cerebrovascular diseases in patients with T2DM. However, ABI is superior to MAU in predicting cardiovascular and cerebrovascular diseases in patients with small and short duration.