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本文报告了一次乙肝流行中6例病人与一批亚临床感染的抗-HBcIgM检测结果。5名亚临床感染儿童经6～7个月随访发现,在抗-HBcIgM转阴或S/N值下降的同时,抗-HBs阳转。结果表明,抗-HBcIgM可以作为在近期内有亚临床感染的一个判断指标。这对人群中乙肝流行病学研究颇有价值。亚临床感染在“窗户期”与抗-HBs刚阳转时的抗-HBc IgM S/N GMV(分别为3.9与1.9),均较临床病例的(6.9与7.4)为低;持续时间也较短。急性乙肝恢复早期,抗-HBs刚阳转时,抗-HBcIgM的S/NGMV可达7.4,提示可能仍有传染性。
This article reports the results of an anti-HBcIgM assay in 6 patients with a subset of subclinical infections in a hepatitis B epidemic. Five sub-clinically infected children were followed up for 6 to 7 months. Anti-HBs yielded positive results when anti-HBcIgM negative or S / N decreased. The results show that anti-HBcIgM can be used as a judgment indicator of subclinical infection in the near future. This is of great value to the epidemiological study of hepatitis B in the population. Anti-HBc IgM S / N GMV (3.9 and 1.9, respectively) in subclinical infection at window versus anti-HBs positive was lower than in clinical cases (6.9 and 7.4), and duration was also lower short. In the early stage of acute hepatitis B recovery, anti-HBc positive S-NGMV reached 7.4 when anti-HBs were positive, suggesting that there may still be infectious.