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目的了解成都市医院腹股沟疝外科手术患者预防用抗生素药物现状,为加强医院管理,促进临床合理应用抗菌药物提供依据。方法采用分层随机抽样方法抽取成都市10家样本医院,并在样本医院中随机抽取2005年外科腹股沟疝手术病例348例,对围手术期预防用抗生素药物情况进行分析评价。结果围手术期预防用抗生素药物存在问题有:(1)初次给药时机不合适,无在麻醉诱导时初次用药者,且绝大多数为术后初次用药(91.95%)。(2)总的用药时间偏长,>48h者达95.98%。(3)不合理用药比例24.14%,选择用药的合理性有待提高。结论应将合理用药纳入医院考评标准和临床医师继续医学教育内容,建立健全临床药师制度,进一步规范临床用药行为。
Objective To understand the status of prophylactic antibiotics in patients undergoing inguinal hernia surgery in Chengdu Hospital and provide the basis for strengthening hospital management and promoting the rational use of antibacterials in clinics. Methods Tensile stratified random sampling method was used to select 10 sample hospitals in Chengdu and 348 cases of surgical inguinal hernia were randomly selected from the sample hospitals in 2005. The situation of perioperative prophylactic antibiotics was analyzed and evaluated. Results The perioperative prophylactic antibiotics had the following problems: (1) The timing of the initial administration was not suitable, and no initial administration was made at the time of induction of anesthesia, and the majority of them were used for the first time after operation (91.95%). (2) The total medication time is long, 95.98%> 48h. (3) irrational drug use rate of 24.14%, the rationality of the choice of medication needs to be improved. Conclusion Rational use of drugs should be included in the hospital evaluation criteria and clinicians to continue the content of medical education, establish and improve the clinical pharmacist system to further standardize clinical drug use behavior.