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多发性硬化病(MS)患者血清或血浆成分的异常引起了许多学者的注意,希望能够更好地了解MS的发病机理,并建立特异而灵敏的诊断和判断预后的方法。本篇综述提供并评论了MS患者血清和血浆中许多成分的异常及脑脊液、红细胞和白细胞中几种成分的异常。非蛋白成分Ⅰ、脂类A、脑苷脂正常情况下,血清中的脑苷脂主要是葡萄糖脑苷脂,少量的半乳糖脑苷脂。相反脑髓鞘和脑脊液(CSF)中半乳糖脑苷脂则占
Abnormal serum or plasma components of patients with multiple sclerosis (MS) have drawn the attention of many scholars in the hope of better understanding the pathogenesis of MS and establishing specific and sensitive methods of diagnosis and prognosis. This review provides and comments on abnormalities in many components of serum and plasma from patients with MS and abnormalities in several components of cerebrospinal fluid, erythrocytes and leukocytes. Non-protein component Ⅰ, lipid A, cerebroside Normal under the condition of cerebrosides in the serum is mainly glucocerebrosidase, a small amount of galactocerebrosidase. In contrast, cerebrospinal fluid and cerebrospinal fluid (CSF) galactocerebroside accounted for