论文部分内容阅读
结节性红斑首先由Willan(1798年)、Wilson(1842年)报告,后经Hebra确定为一独立的疾病。因为本病具有临床特征,诊断并不难,但其病因和发病机理至今仍不甚明瞭。以往一直将结节性红斑归类于红斑性疾病或脂膜炎,然而最近几年通过皮肤损害的病理组织和免疫荧光的研究,发现和血管炎的关系甚为密切。一、临床表现:主要是在小腿伸侧,也可在大腿、前臂、颜面对称出现限局性硬结性红斑,压痛明显,每个损害可持续2～4周,
Nodular erythema was first reported by Willan (1798), Wilson (1842) and later by Hebra as an independent disease. Because of the clinical features of the disease, the diagnosis is not difficult, but its etiology and pathogenesis remains unclear. In the past, erythema nodosum has been classified as erythema or panniculitis. However, in recent years, studies on pathological tissue and immunofluorescence of skin lesions have found that there is a close relationship between vasculitis and vasculitis. First, the clinical manifestations: mainly in the lower leg extensor, but also in the thigh, forearm, facial symmetry appear limited focal scleroderma, tenderness significantly, each damage sustainable 2 to 4 weeks,