对营养代谢组学—技术思考(英文)

• 作 者: 黄卓睿 黄秀莹 李德强
• 机 构: Division of Nutritional Sciences,Postgraduate Program in Clinical Biochemistry and Molecular Biology
• 出 处: 营养健康新观察
• 发表日期: 2007年03期
• 关键词: intake nutrient nutritional pharmacology profiling 代谢组学 elucidate metabolite ret

Metabonomics has been applied successfully in different research fields such as toxicology and pharmacology(1-7).However,application of metabonomics in nutritional research is still at infancy stage of development.Historically outcome measurement as an analytical approach has been widely used in nutritional research.This approach provides direct evidence linking the effect of nutrient intake on heath and disease.However,outcome measurement does not elucidate the underlying mechanistic effect of a nutrient intake

Metabonomics has been applied successfully in different research fields such as toxicology and pharmacology (1-7). However, application of metabonomics in nutritional research is still at infancy stage of development. Physically outcome measurement as an analytical approach has been widely used in trophic research .This approach provides direct evidence linking the effect of nutrient intake on heath and disease. Yetever, outcome measurement does not elucidate the underlying mechanistic effect of a nutrient intake.