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目的比较腹腔镜辅助远端胃癌D2根治术与传统开腹术对老年患者免疫功能及临床疗效的影响。方法选取2012年10月至2014年10月东莞市人民医院收治的胃癌并择期行根治术患者共70例为研究对象,按手术方法不同将入组患者分为对照组32例(行开腹手术)和观察组38例(行腹腔镜手术)。比较各组患者切口长度、术中出血量、手术时间、术后肛门排气时间、住院时间、淋巴结清扫数及外周血Ig G、Ig M水平。结果观察组患者切口长度、术中出血量、手术时间、术后肛门排气时间及住院时间均小于对照组,两组比较差异有统计学意义(P<0.05);两组患者淋巴结清扫个数比较差异未见统计学意义(P>0.05)。观察组患者术后外周血Ig G、Ig M水平均显著高于对照组,两组比较差异有统计学意义(P<0.05)。结论行腹腔镜辅助远端胃癌D2根治术具有创伤少、恢复快、免疫功能影响小等特点,其效果优于传统开腹手术。
Objective To compare the effects of laparoscopic-assisted distal gastric cancer D2 and conventional laparotomy on immune function and clinical efficacy in elderly patients. Methods Seventy patients with gastric cancer admitted to Dongguan People’s Hospital from October 2012 to October 2014 were enrolled in this study. All patients were divided into control group (32 cases) undergoing open surgery ) And observation group 38 cases (laparoscopic surgery). The incision length, intraoperative blood loss, operation time, postoperative anal exhaust time, hospitalization time, number of lymph node dissection and peripheral blood Ig G, Ig M levels were compared between groups. Results The incision length, intraoperative blood loss, operation time, postoperative anal exhaust time and hospital stay in the observation group were less than those in the control group, with significant difference between the two groups (P <0.05). The number of lymph node dissection The difference was not statistically significant (P> 0.05). The levels of Ig G and Ig M in the peripheral blood of patients in the observation group were significantly higher than those in the control group, with significant difference between the two groups (P <0.05). Conclusion Laparoscopic-assisted D2 distal root canal surgery has the advantages of less trauma, faster recovery and less influence of immune function, which is superior to traditional laparotomy.