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目的:观察中药茵栀黄口服液对新生儿黄疸的预防作用及不良反应。方法:将400例足月新生儿分为观察组(200例)及对照组(200例),观察组于生后第2天给予茵栀黄口服液预防治疗,而对照组口服纯净水,比较两组新生儿黄疸出现例数、平均出现时间、黄疸需光疗数、呕吐发生率、腹泻发生率。结果:观察组黄疸出现时间晚于对照组,出现例数少于对照组、黄疸需光疗数少于对照组,差异均有统计学意义(P<0.05),呕吐及腹泻发生率与对照组比较无统计学差异(P>0.05)。结论:生后早期应用茵栀黄口服液对新生儿黄疸有一定的预防作用,且无明显不良反应,可减少新生儿黄疸的发生。
Objective: To observe the preventive effect and adverse reactions of Yinzhihuang Oral Liquid on neonatal jaundice. Methods: 400 full-term newborns were divided into observation group (n = 200) and control group (n = 200). The observation group was given Yinzhihuang oral solution on the second day after birth, while the control group was given pure water Two cases of neonatal jaundice cases, the average time, jaundice need light therapy, vomiting, diarrhea incidence. Results: The incidence of jaundice in the observation group was later than that in the control group, with fewer cases than the control group and fewer jaundice than the control group (P <0.05). The incidence of vomiting and diarrhea was significantly lower than that of the control group No statistical difference (P> 0.05). Conclusion: The application of Yinzhihuang Oral Liquid in early life after neonatal jaundice has a certain preventive effect, and no obvious adverse reactions, can reduce the incidence of neonatal jaundice.