论文部分内容阅读
目的研究医院感染的金黄色葡萄球菌的耐药状况，指导临床合理用药。方法对该院医院感染的标本分离出的91倒金黄色葡萄球菌（SA）进行药敏试验和β-内酰胺酶测试，然后分析。结果91株SA中，耐甲氧西林金黄色葡萄球菌（MRSA）有58株，占63．7％；甲氧西林敏感金黄色葡萄球菌（MSSA）有33株，占36．3％。91株SA对万古霉素的耐药率均为0，MRSA对15种抗生素耐药率超过50％的12种，而MSSA对15种抗生素耐药率超过50％的只有6种；91株机的产β-内酰胶酶的产酶率是56％，MRSA和MSSA的产酶率分别是56.9％和54．5％。结论该院MRSA的高检出率和高耐药率应引起临床的重视，万古霉素目前仍是治疗MRSA感染的最有效抗生素，该院的MRSA和MSSA产β-内酰胺酶的产酶率没有什么差异。
Objective To study the drug-resistant status of hospital-acquired Staphylococcus aureus and to guide clinical rational use of drug. Methods Ninety-four S. aureus isolates from hospital-acquired nosocomial infections were tested for susceptibility and beta-lactamase and then analyzed. Results There were 58 strains of methicillin-resistant Staphylococcus aureus (MRSA) in 91 isolates, accounting for 63.7%. 33 strains of methicillin-sensitive Staphylococcus aureus (MSSA) accounted for 36.3%. Ninety-one strains of SA were resistant to vancomycin, 0 of them were resistant to 15 strains of MRSA, 50 strains of MRSA were resistant to 15 strains of antibiotics, while 6 strains of MSSA were more than 50% The yield of β-lactamase producing enzyme was 56%, and the yield of MRSA and MSSA was 56.9% and 54.5%, respectively. Conclusions The high detection rate and high drug resistance rate of MRSA in this hospital should be paid more attention. Vancomycin is still the most effective antibiotic for MRSA infection. The enzyme production rate of β-lactamase produced by MRSA and MSSA in this hospital There is no difference.