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目的 研究中年 2型糖尿病 (NIDDM)患者的记忆功能和糖尿病的关系 ,以更有效地教育和治疗患者。方法 对象为中年 (4 0～ 6 0岁 ) NIDDM患者和人口学因素相似的非糖尿病人各 30名 ,排除可能影响记忆功能的脑血管疾病、药物和酒精滥用、痴呆和严重的精神疾病等 ,糖尿病人测查当日均无低血糖发作。采用韦氏记忆量表测查记忆功能 ;EPQ、SAS、SDS测查人格和情绪状态 ;患者和对照组各 11人做脑血流灌注显像检查 (SPECT)。结果 糖尿病组记忆测验各项成绩均低于对照组 (P <0 .0 5 )、焦虑和抑郁情绪较对照组严重 (P <0 .0 5 )。SPECT显示 NIDDM患者确实存在着局部脑血流的低灌注。结论中年 NIDDM患者确实存在记忆力的下降 ,局部脑血流的低灌注可能是原因之一。患者的心身因素与记忆功能相关。心理健康可以促进记忆等认知功能的提高。医护人员及家属应该对此有所了解并采取相应的治疗和教育措
Objective To study the relationship between memory function and diabetes in patients with type 2 diabetes mellitus (NIDDM) in middle age in order to educate and treat patients more effectively. METHODS: Subjects were middle-aged (40 to 60 years old) NIDDM patients and 30 non-diabetic demographic factors, excluding cerebrovascular disease, drug and alcohol abuse, dementia and severe mental illness, which may affect memory function , No hypoglycemic episodes on the day of diabetes test. Memory function was measured by Wechsler memory scale. Personality and emotional status were measured by EPQ, SAS and SDS. Cerebral perfusion imaging (SPECT) was performed in 11 patients in each group. Results The score of memory test in diabetic group was lower than that in control group (P <0.05), and anxiety and depression were more serious than those in control group (P <0.05). SPECT shows that there is indeed a low perfusion of regional cerebral blood flow in NIDDM patients. Conclusion Middle-aged patients with NIDDM do have memory loss, and local hypoperfusion of cerebral blood flow may be one of the reasons. The patient’s psychosomatic factors are related to memory function. Mental health can promote cognitive functions such as memory. Health care workers and their families should understand this and take appropriate treatment and education measures