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目的探讨皮角的临床和组织病理学特点。方法对30例皮角患者的临床及组织病理学资料进行回顾性分析。结果 30例患者中,男18例(60.00%),女12例(40.00%);平均患病年龄67.9岁(20~94岁);病程1个月~32年,平均32.7个月。26例(86.67%)发生于曝光部位。组织病理检查均可见高度的角化过度,间有程度不等的角化不全,角质层呈山峰样隆起;基底部原发病变组织学改变:有70.00%为良性病变,30.00%为癌前或癌性病变;在良性病变中,病毒疣占61.90%,脂溢性角化病占33.33%;在癌前或癌性病变中,日光性角化病占77.78%;癌性病变仅1例,为鳞癌。63.33%病例的组织病理可见真皮内有不同程度的胶原纤维日光弹力变性改变。结论皮角好发于老年人,以头面部等曝光部位居多;皮角与癌前或癌性病变相关,完整切除皮损并行组织病理学检查十分重要。
Objective To investigate the clinical and histopathological features of skin angle. Methods The clinical and histopathological data of 30 cases of skin angle patients were retrospectively analyzed. Results Among the 30 patients, 18 (60.00%) were males and 12 (40.00%) were females. The mean age at onset was 67.9 years (20-94 years). The course of disease ranged from 1 month to 32 years with an average of 32.7 months. 26 cases (86.67%) occurred in the exposure site. Histopathological examination showed a high degree of hyperkeratosis, ranging from varying degree of keratosis, keratosis layer was mountain-like uplift; basal primary lesions histological changes: 70.00% for benign lesions, 30.00% of pre-cancerous or Cancerous lesions; in benign lesions, viral warts accounted for 61.90%, seborrheic keratosis accounted for 33.33%; in precancerous or cancerous lesions, solar keratosis accounted for 77.78%; only 1 case of cancerous lesions, For squamous cell carcinoma. The histopathology of 63.33% cases showed that the dermis had different degree of daylight elastic degeneration of collagen fibers. Conclusion The skin angle is predominant in the elderly, with the exposure of the head and face mostly. The skin angle is related to the precancerous or cancerous lesions. Complete histopathological examination of the lesions is very important.