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目的:探讨宫颈糜烂与生殖道高危型人乳头状瘤病毒(HR-HPV)感染之间的关系。方法:选择确诊为宫颈糜烂患者92例进行HR-HPV检测,对不同程度宫颈糜烂患者的HR-HPV感染情况进行比较。结果:宫颈I度糜烂27例中感染HRHPV3例,感染率11.1%;宫颈II度糜烂36例中感染HR-HPV13例,感染率36.1%;宫颈III度糜烂29例中感染HR-HPV14例,感染率48.3%。宫颈单纯型糜烂30例中感染HR-HPV 5例,感染率16.7%;宫颈颗粒型糜烂38例中感染HR-HPV9例,感染率23.6%;宫颈乳头型糜烂24例中HPV阳性13例,感染率54.1%。宫颈I、II、III度糜烂患者的HR-HPV感染率差异有统计学意义(P<0.05),宫颈颗粒型糜烂和宫颈乳头型糜烂与宫颈单纯型糜烂HR-HPV感染率差异有统计学意义(P<0.05),而宫颈颗粒型糜烂和宫颈乳头型糜烂HR-HPV感染率差异无统计学意义(P>0.05)。结论:宫颈糜烂与生殖道HR-HPV感染之间有着十分的相关性,随着宫颈糜烂程度的增加,HR-HPV阳性感染越来越多,所以有必要关注宫颈糜烂患者的HR-HPV感染情况,尤其是病情严重的宫颈糜烂患者,以防止宫颈癌的发生。
Objective: To investigate the relationship between cervical erosion and genital high risk human papilloma virus (HR-HPV) infection. Methods: 92 cases diagnosed as cervical erosion were selected for HR-HPV testing. HR-HPV infection of patients with different degrees of cervical erosion were compared. Results: Cervical I degree erosion in 27 cases of HRHPV infection in 3 cases, the infection rate was 11.1%; Cervical II degree erosion in 36 cases of HR-HPV infection in 13 cases, the infection rate was 36.1%; Cervical III degree erosion in 29 cases of HR-HPV infection in 14 cases, infection Rate of 48.3%. Cervical simple erosion in 30 cases of HR-HPV infection in 5 cases, the infection rate was 16.7%; cervical granulo-erosion in 38 cases of HR-HPV infection in 9 cases, the infection rate was 23.6%; cervical papillary erosion in 24 cases of HPV-positive in 13 cases, infection Rate of 54.1%. There were significant differences in HR-HPV infection rates between I, II and III patients with cervical erosions (P <0.05). There was significant difference in HR-HPV infection rate between cervical granular erosion and cervical papillary erosion and cervical simple erosion (P <0.05). However, there was no significant difference in HR-HPV infection rate between cervical granular erosion and cervical papillary erosion (P> 0.05). Conclusion: Cervical erosion and reproductive tract HR-HPV infection has a very close relationship between, with the increase of cervical erosion, HR-HPV positive infection more and more, so it is necessary to pay attention to cervical erosion in patients with HR-HPV infection , Especially in patients with severe cervical erosion, in order to prevent the occurrence of cervical cancer.