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目的探讨经子宫动脉药物灌注、栓塞联合口服米非司酮治疗宫颈妊娠在临床中的应用价值。方法 21例宫颈妊娠患者均采用Seldinger技术行子宫动脉造影,甲氨蝶呤80 mg药物灌注,用适当大小明胶海绵颗粒栓塞子宫动脉,联合口服米非司酮;术后阴道少量流血,复查血β-绒毛膜促性腺激素(β-HCG)和孕酮变化。结果 21例宫颈妊娠患者介入治疗术后联合口服米非司酮,血β-HCG和孕酮9~21 d恢复正常,超声检查孕囊消失,术后未出现子宫穿孔、宫腔粘连等并发症。结论子宫动脉药物灌注、栓塞联合口服米非司酮治疗宫颈妊娠疗效确切,并发症少,取得了良好效果。
Objective To investigate the clinical value of uterine artery drug infusion and embolization combined with oral mifepristone in the treatment of cervical pregnancy. Methods 21 cases of cervical pregnancy were treated with Seldinger technique uterine artery angiography, methotrexate 80 mg drug infusion, with the appropriate size gelatin sponge particles embolization uterine artery, combined with oral mifepristone; a small amount of postoperative vaginal bleeding, blood β - Chorionic gonadotropin (β-HCG) and progesterone changes. Results Twenty-one patients with cervical pregnancy were treated with oral mifepristone, and serum β-HCG and progesterone returned to normal after 9 to 21 days. The gestational sac disappeared after ultrasound examination. No complications such as uterine perforation and intrauterine adhesions occurred after operation . Conclusion Uterine artery drug infusion, embolization combined with oral mifepristone treatment of cervical pregnancy exact effect, fewer complications, and achieved good results.