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脑灰质异位症的主要临床表现或首发症状常为癫痫发作。据我院CT室不完全统计,近10年里诊断30例。现将资料完整的8例报告如下。 临床资料:本组男5例,女3例;年龄13～28岁。有反复抽搐发作史1～10年,均无脑外伤、肿瘤及癫痫家族史。首发症状为抽搐发作,其中大发作5例、部分性发作兼大发作2例、复杂部分性发作1例。多数每天发作1～3次,个别为每月2～4次。神经系统检查:轻偏瘫且有病理反射1例,余无异常发现。简易智能检查仅2例智能低下(与抽搐频繁发作有关)。经治疗,6例好转,但抗痫药不能减量;智能低下的2例病情渐恶化。脑电图检查:7例中、重度异常,1例“基本正常”,但24小时脑电连续监测有尖慢综合波阵发性发放。诱发电位检查:SEP与VEP均见异常,但无特异性。CT检查:7例可见异位的灰质突出于白质内,CT值与周围脑灰质相同;2例需与脑瘤鉴别而行增强扫描,但未见强化。
The main clinical manifestations of gray matter or the first symptom of seizures. According to our hospital incomplete CT statistics, diagnosis of 30 cases in the past 10 years. 8 cases are now complete report as follows. Clinical data: The group of 5 males and 3 females; aged 13 to 28 years old. Have a history of repeated seizures 1 to 10 years, no brain trauma, cancer and family history of epilepsy. The first symptom was convulsive seizures, including 5 cases of major episodes, partial and major episodes in 2 cases, complex partial seizures in 1 case. The majority of attacks 1 to 3 times a day, some 2 to 4 times per month. Neurological examination: hemiparesis and pathological reflex in 1 case, I found no abnormalities. Simple intelligent examination only 2 cases of mental retardation (associated with frequent episodes of seizures). After treatment, 6 cases improved, but anti-epileptic drugs can not be reduced; two cases of mental retardation worsened. EEG examination: 7 cases of moderate and severe abnormalities, 1 case of “basic normal”, but 24 hours continuous monitoring of EEG intermittent sporadic polygovial issuance. Evoked potentials: SEP and VEP were abnormal, but non-specific. CT examination: seven cases of ectopic gray matter prominence in the white matter, CT values and peripheral gray matter the same; 2 cases with brain tumor differential line scan, but no enhancement.