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[ 研究背景]1996 年7 ~9 月间延边地区曾流行病毒性脑炎、脑膜炎,此间收治313 例此病患儿.[ 病例报告]313 例均为急性发病,男略多于女;平均年龄9 岁,高峰在6 ~10 岁;均有发热、头痛,以低度、中度热为主,多数伴恶心、呕吐;意识障碍以嗜睡为主;多数有脑膜刺激征.多数脑脊液改变,末梢血淋巴细胞升高.脑脊液、粪便中分离出肠道病毒.平均病程14d,愈后较好.[ 讨论] 本次流行的病毒性脑炎系肠道病毒感染所致,发病急,多见于学龄儿童,临床表现相对轻,病程短,预后较好.
[Background] From July to September 1996, epidemic encephalitis and meningitis were endemic in Yanbian area, and 313 children with this disease were admitted here. [Case Reports] 313 cases were acute onset, slightly more men than women; average age 9 years old, the peak at 6 to 10 years; have fever, headache, low to moderate fever, most with nausea and vomiting ; Disturbance of consciousness to drowsiness; most have meningeal irritation. Most cerebrospinal fluid changes, peripheral blood lymphocytes increased. Cerebrospinal fluid, feces isolated from enterovirus. The average duration of 14d, better after healing. [Discussion] The epidemic of viral encephalitis is caused by enterovirus infection, the incidence of acute, more common in school-age children, clinical manifestations are relatively light, short duration, the prognosis is good.