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本文是对1962—1973年在承德地区,地方性甲状腺肿与地方性克汀病防治、病因与发病机制研究的初步调查报告。食盐加碘(1/20,000)试验,可使弥漫型Ⅱ、Ⅲ度甲状腺肿缩小至Ⅰ度。孕妇及婴儿服用甲状腺片,有可能预防地方性克汀病的发生。承德地区地方克汀病和甲状腺机能低下临床表现较新疆阿克苏地区及非洲扎伊尔所见为轻,故用甲状腺片代替治疗,疗效不明显。调查中发现该地食物中缺钴,与患病有否关系尚不详。作者认为地方性克汀病的发生可能与母亲怀孕期间碘供不足有关。如进行营养治疗及积极教育训练,对体格发育、体力增强、性成熟及一定智力发育和聋哑程度可能有所改善。是今后努力方向。
This article is a preliminary investigation of the prevention and treatment of endemic goiter and endemic cretinism in Chengde from 1962 to 1973. Salt iodization (1 / 20,000) test, diffuse type Ⅱ, Ⅲ degree goiter can be reduced to Ⅰ degree. Pregnant women and babies taking thyroid tablets, it is possible to prevent the occurrence of endemic cretinism. Chengde area where cretinism and hypothyroidism clinical performance than in Xinjiang Aksu region and Africa Zai Er see light, so the thyroid tablets instead of treatment, the effect is not obvious. The survey found that the absence of cobalt in the food, and the relationship between the disease is not yet known. Authors believe that the occurrence of endemic cretinism may be related to the mother during pregnancy iodine deficiency related. Such as nutrition treatment and active education and training, physical development, physical strength, sexual maturity and certain mental development and deaf-mute may be improved. Is the direction of future efforts.