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1988年9月14日～10月2日,16名美国人赴博茨瓦纳旅游,其中12例在该地区有疫水接触史。在旅游后5周内11人出现疲劳、发热、出汗、寒战、头痛和胃肠道不适等症状。症状持续1～30天(平均8天)。6例曾作外周血象检查,见嗜酸酸粒细胞增高。11例粪检9例中发现少量具曼氏血吸虫虫卵和罗氏血吸虫虫卵特征的虫卵。3例尿检虫卵阴性。15例旅游者的血清标本,抗血吸虫血清抗体均呈阳性;而1例未采血者粪检曼氏血吸虫卵阳性。对虫卵阳性和/或血清抗体阳性者均用吡喹酮单剂口服(40mg/kg),治疗后症状消失,无严重副作用。
From September 14 to October 2, 1988, 16 Americans traveled to Botswana, 12 of whom had a history of contagious water in the area. Within five weeks of travel, 11 experienced symptoms of fatigue, fever, sweating, chills, headaches and gastrointestinal upset. Symptoms last 1 to 30 days (average 8 days). 6 cases had peripheral blood examination, see eosinophils increased. A small amount of eggs of Schistosoma mansoni eggs and schistosoma peregrines eggs were detected in 11 cases of stool samples. 3 cases of urinary insects eggs negative. Serum specimens of 15 tourists, anti-schistosoma serum antibodies were positive; and 1 case of non-lancing of man-tested Schistosoma mansoni egg-positive. Praziquantel single oral (40mg / kg) positive for egg and / or serum antibody positive symptoms disappear after treatment without serious side effects.