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[目的]观察血痹丹合剂治疗糖尿病周围神经病变疗效。[方法]使用前瞻性设计方法,对40例住院患者常规控制血糖及合并症,血痹丹合剂(黄芪400g,桂枝150g,干姜120g,当归150g,川芎100g,赤芍200g,生地黄250g,丹参、地龙各200g,红花150g,延胡索200g,鸡血藤400g,山药200g,肉桂50g。加药量3倍量水浸泡2h,煎煮2次。首次2h,过滤,滤液备用。再加入药量2倍量水煎煮1h,过滤,合并两次滤液,滤液浓度不低于1.03(50℃),加入苯甲酸钠3g,搅拌使溶解,煮沸,静置12h,取上清液调制成1000mL,分装)早餐前晚餐后各服30mL。治疗期间嘱患者不再服用其他治疗糖尿病神经病变药物,出现不良反应及时反映,病情变化及时处理。连续治疗2周为1疗程。观测临床症状、临床症状积分、不良反应。连续治疗2疗程,判定疗效。[结果]临床治愈2例,显效23例,有效14例,无效1例,总有效率97.50%。[结论]血痹丹合剂联合西药治疗糖尿病周围神经病变,疗效满意,无副作用,值得推广。
[Objective] To observe the therapeutic effect of Xuebidedan Mixture on diabetic peripheral neuropathy. [Methods] A total of 40 inpatients were randomly divided into control group and control group. Blood Glucose and Complications, Blood Bi Dan Mixture (Astragalus 400g, Guizhi 150g, Dry Ginger 120g, Angelica 150g, Chuanxiong 100g, Radix Paeoniae Rubra 200g, Radix Rehmanniae 250g , Salvia, earthworm each 200g, safflower 150g, corydalis 200g, Millettia 400g, yam 200g, cinnamon 50g. Dosing 3 times the amount of water soak 2h, boiling 2 times for the first time 2h, filtration, the filtrate spare. Add 2 times the amount of water decoction 1h, filtered and the filtrate twice, the filtrate concentration of not less than 1.03 (50 ° C), sodium benzoate 3g, stirring to dissolve, boil, stand 12h, the supernatant was prepared 1000mL, packaging) After breakfast, each serving 30mL. During the Zhu Huanzhe no longer take other drugs for the treatment of diabetic neuropathy, adverse reactions appear in a timely manner, timely treatment of changes in condition. Continuous treatment for 2 weeks for a course of treatment. Observation of clinical symptoms, clinical symptom scores, adverse reactions. Continuous treatment of 2 courses to determine the efficacy. [Results] 2 cases were clinically cured, 23 cases were markedly effective, 14 cases were effective, 1 case was ineffective and the total effective rate was 97.50%. [Conclusion] The combination of Xuebide Dan and western medicine in the treatment of diabetic peripheral neuropathy has satisfactory curative effect and no side effects and is worth promoting.