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目的观察两种不同联合用药在人工流产术中的效果及不良反应。方法选取2012年1月至6月行人工流产的受术者160例,随机分成2组:Ⅰ组80例,予术前静脉注射间苯三酚40mg,再静脉推注安定10mg;Ⅱ组80例,予术前静脉注射瑞芬太尼1μg/kg,再静脉滴注异丙酚1.5mg/kg维持至手术结束,比较2组的镇痛、扩张宫颈等效果及不良反应。结果Ⅰ组宫颈扩张总有效率92.50%优于Ⅱ组81.25%(P<0.05),术中及术后流血量差异有统计学意义(P<0.01),2组镇痛效果及人工流产综合征等并发症的发生差异无统计学意义。结论在人工流产术中使用间苯三酚联合安定或瑞芬太尼联合异丙酚,均有明显镇痛效果,而间苯三酚联合安定扩张宫颈效果较瑞芬太尼联合异丙酚显著,且术中及术后出血量较少。
Objective To observe the effects and adverse reactions of two different combinations in artificial abortion. Methods 160 patients who underwent induced abortion from January 2012 to June 2012 were randomly divided into two groups: group Ⅰ (n = 80), preoperative intravenous injection of 40mg phloroglucinol and intravenous bolus 10mg, group Ⅱ For example, preoperative intravenous remifentanil 1μg / kg, and then intravenous propofol 1.5mg / kg maintained until the end of surgery, the two groups of analgesic, cervical dilatation and other adverse reactions. Results The total effective rate of cervical dilatation in group Ⅰ was 92.50%, which was significantly higher than that in group Ⅱ (81.25%) (P <0.05). There was a significant difference in bleeding volume during and after operation (P0.01). The analgesic effect and abortion syndrome Complications such as the difference was not statistically significant. Conclusions The use of phloroglucinol or fentanyl combined with propofol in induced abortion have obvious analgesic effect, while the effect of phloroglucinol combined with diazepam on cervical dilation is more significant than remifentanil combined with propofol , And less blood loss during and after surgery.