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目的:了解肝病患者围介入术期抗菌药应用情况,为加强抗菌药的合理使用和规范管理提供依据。方法:取2009年6月～2010年1月肝病科介入手术患者病历资料121份,对围介入术期预防性使用抗菌药的现状进行合理性分析。结果:121例围介入术期患者,其中肝炎病毒感染者114例(94.21%);受术者全部使用了抗菌药,共涉及4类11种,使用率100.00%;抗菌药使用总例次145例,使用疗程6～14 d,平均(8.07±2.32)d,≤48h的2例。未感染患者在术前0.5～2 h预防用药例数为0,术后以预防为目的的用药109例(75.18%)。结论:围介入术期抗菌药使用存在用药时间过长、时机掌握不合理等问题需进一步规范管理,促进抗菌药合理使用。
Objective: To understand the application of antibacterials during the perioperative period of patients with liver diseases, and to provide basis for strengthening the rational use and standardized management of antibacterials. Methods: From June 2009 to January 2010, 121 cases of patients with liver disease interventional surgery were included in this study. The rationality of prophylactic use of antibacterial agents during the perioperative period was analyzed. Results: Of the 121 patients who underwent perioperative intervention, 114 (94.21%) patients were infected with hepatitis B virus. All the patients were treated with antimicrobial agents, involving 11 types and 11 types, with a utilization rate of 100.00%. The total number of antibacterials used was 145 Cases, the use of treatment 6 ~ 14 d, the average (8.07 ± 2.32) d, ≤ 48h in 2 cases. In uninfected patients, there were 109 cases (75.18%) of prophylaxis cases with prophylaxis for 0.5 ~ 2 hours before surgery and 109 days after prophylaxis. Conclusion: The use of antimicrobial agents in the perioperative period is too long and the timing is not reasonable to further standardize the management and promote the rational use of antimicrobial agents.