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我们以北京医科大学附属人民医院乳腺病防治中心16例接受手术治疗的乳腺癌患者为研究对象,通过测定末梢血细胞免疫指标,对其机体免疫功能的变化与手术打击影响的关联性进行了分析观察.16例中包括乳腺癌改良根治术15例,乳腺癌局广切加腋窝淋巴结清扫术1例;病理类型分为乳腺浸润性导管癌12例,乳腺浸润性小叶癌2例,乳腺单纯癌2例;临床分期为:Ⅰ期6例,Ⅱ期6例,Ⅲ期4例.我们对16例患者于术前第3天及术后第3天分别提取末梢血淋巴细胞,使用单克隆抗体进行免疫染色,检测CD3、CD4、CD8、
We studied 16 breast cancer patients who underwent surgical treatment at the Breast Disease Prevention Center of the People’s Hospital of Beijing Medical University as the research object. The peripheral blood cell immune parameters were measured, and the correlation between the changes in the immune function of the body and the impact of surgical strike was analyzed. The 16 cases included 15 cases of modified radical mastectomy for breast cancer, and 1 case of axillary lymph node dissection for breast cancer. The pathological types included 12 cases of breast invasive ductal carcinoma, 2 cases of breast infiltrating lobular carcinoma, and 2 cases of simple breast cancer. Cases: Clinical stage: 6 cases in phase I, 6 in phase II, and 4 in phase III. We extracted peripheral blood lymphocytes in 16 patients on the 3rd day before surgery and on the 3rd day after surgery, using monoclonal antibodies. Immunostaining, detection of CD3, CD4, CD8,