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目的 研究小儿非细菌性下呼吸道感染病原体种类及感染特点。方法 选择下呼吸道感染住院患儿 186例 ,采用ELISA方法分别检测患儿急性期及恢复期流感病毒A、流感病毒B、副流感病毒、呼吸道合胞病毒、腺病毒、肺炎支原体、肺炎衣原体血清抗体。用PCR技术检测肺炎支原体、肺炎衣原体。结果 186例患儿非细菌性病原体检出率为 4 2 5 %。检出流感病毒A 12例 ( 6 4 % )、流感病毒B 5例 ( 2 7% )、副流感病毒 3例 ( 1 6 % )、呼吸道合胞病毒 2 3例 ( 12 4 % )、腺病毒 4例 ( 2 2 % )、肺炎支原体 2 6例 ( 13 9% )、肺炎衣原体 6例 ( 3 2 % )。结论 非细菌性病原体在小儿下呼吸道感染中占重要地位 ,病原学诊断对指导临床治疗有重要价值
Objective To study the types of non-bacterial lower respiratory tract infection in children and the characteristics of infection. Methods A total of 186 hospitalized children with lower respiratory tract infection were enrolled in this study. Serum anti-influenza A, influenza B, parainfluenza, respiratory syncytial virus, adenovirus, Mycoplasma pneumoniae and Chlamydia pneumoniae were detected by ELISA in children at acute and convalescent stages . PCR detection of Mycoplasma pneumoniae, Chlamydia pneumoniae. Results The detection rate of non-bacterial pathogens in 186 children was 42.5%. 12 cases (6.4%) of influenza virus A, 5 cases (27%) of influenza virus B, 3 cases (16%) of parainfluenza virus, 23 cases (12.4%) of respiratory syncytial virus, adenovirus 4 cases (22%), 26 cases of Mycoplasma pneumoniae (13 9%) and 6 cases of Chlamydia pneumoniae (32%). Conclusion Non-bacterial pathogens play an important role in pediatric lower respiratory tract infection. Etiologic diagnosis is of great value in guiding the clinical treatment