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注射剂混合给药已经经常化,β-内酰胺类抗生素是常用药,而且给药量大,为了保证安全用药,本文研究β-内酰胺类抗生素和叔胺类药物吩噻嗪类及三环类抗抑郁药在水溶液中的相互作用。把2×10~(-2)M 的β-内酰胺类抗生素和叔胺类药物的枸橼酸缓冲液(pH=4.5,μ=0.6,KC(?))各2ml 混合后,在室温下放置,立即观察其外观变化。结果大多数配合溶液生成了白色沉淀或白色浑浊。在叔胺类药物中以氯丙嗪、氯丙咪嗪;在β-内酰胺类抗生
Injection mixing has been normalized, β-lactam antibiotics are commonly used drugs, and the dose, in order to ensure safe medication, this study β-lactam antibiotics and tertiary amine phenothiazines and tricyclics Antidepressants Interactions in Aqueous Solutions. Mix 2 ml of 2 ml each of 2 x 10 ~ (-2) M β-lactam antibiotics and tertiary amine citrate buffer (pH = 4.5, μ = 0.6, KC Place, immediately observe the appearance of changes. As a result, most of the complexing solutions formed a white precipitate or white turbidity. In tertiary amines in the chlorpromazine, clomipramine; in β-lactam antibiotics