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目的探究甲状腺素辅助治疗老年慢性重症心力衰竭的临床疗效。方法 68例老年慢性重症心力衰竭患者,随机分为对照组和治疗组,各34例。对照组患者均采用临床常规药物治疗,治疗组患者均采用甲状腺素辅助常规药物治疗,观察比较两组患者治疗效果。结果治疗组患者治疗总有效率为94.1%,对照组为73.5%,两组患者治疗总有效率比较差异有统计学意义(P<0.05);治疗后治疗组患者血清总三碘甲腺原氨酸(T_3)、血清总甲状腺素(T_4)和促甲状腺激素(TSH)等指标与治疗前相比均显著改善(P<0.05),对照组患者T_3、T_4和TSH指标水平与治疗前比较差异无统计学意义(P>0.05),且两组患者甲状腺水平组间比较差异有统计学意义(P<0.05)。结论老年慢性重症心力衰竭采用甲状腺素辅助常规治疗,可有效缓解患者临床症状,改善甲状腺水平,治疗效果良好,值得临床推广。
Objective To investigate the clinical effect of thyroxine in the treatment of senile chronic severe heart failure. Methods Sixty-eight elderly patients with chronic severe heart failure were randomly divided into control group and treatment group, with 34 cases in each group. The control group patients were treated with routine clinical drugs, the treatment group were treated with thyroxine conventional drugs, observed and compared the therapeutic effect of two groups of patients. Results The total effective rate was 94.1% in the treatment group and 73.5% in the control group. The total effective rate of the two groups was statistically significant (P <0.05). After treatment, the serum total triiodothyronine The indexes of T_3, T_4 and TSH were significantly improved compared with that before treatment (P <0.05). The levels of T_3, T_4 and TSH in control group were significantly lower than those before treatment There was no significant difference between the two groups (P> 0.05), and the difference between the two groups was statistically significant (P <0.05). Conclusions Thyroxine-aided conventional treatment of senile chronic severe heart failure can effectively relieve the clinical symptoms and improve the thyroid gland level, and the treatment effect is good, which is worthy of clinical promotion.