姜黄素对免疫细胞及细胞因子的作用研究进展

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姜黄素(curcumin)是从中药姜黄(curucuma Longa L.)中提取的酚性物质,药理研究发现姜黄素具有免疫调节的作用,它能够调整T细胞、B细胞、巨噬细胞、自然杀伤细胞和树状突细胞的活性:还能够调整多种炎性细胞因子的表达及其介导的作用,包括肿瘤坏死因子、白介素-1、白介素-2、白介素-6等.目前已尝试将姜黄素用于阿耳茨海默氏病、哮喘、类风湿关节炎等与免疫异常相关的疾病.随着在细胞因子水平及分子水平对姜黄素免疫调节作用的进一步阐明,姜黄素对免疫系统疾病的治疗前景将十分光明.
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