论文部分内容阅读
本文对81名正常人和76名接触苯乙烯工人血、呼出气及空气苯乙烯浓度进行检测。正常人中,95%的血样品中能检出苯乙烯,平均浓度为血中2.2nmol/L,肺泡气0.03nmolC/L,空气0.06nmol/L。吸烟者与非吸烟者间苯乙烯水平无显著差异。95%范围上限值为血中5nmol/L,肺泡气0.07nmol/L,空气0.15nmol/L。工人接触苯乙烯平均浓度为2μmol/L,班末血中苯乙烯浓度为12μmol/L,血中浓度在周四(16μmol/L)显著高于周一(11μmol/L)水平。在次日晨血样本也有类似的差异(分别为0.6和1.2μmol/L)。班末及次日晨血和空气浓度有显著相关。接触者次日晨血中浓度显著高于正常人。其血中半减期3.9小时。由此可见,次日晨血中苯乙烯作为职业接触生物监测指标适用于群体和个体水平。
In this paper, 81 normal and 76 workers exposed to styrene blood, exhaled breath and air styrene concentration were detected. Normal people, 95% of the blood samples can be detected in the styrene, the average concentration of blood 2.2nmol / L, alveolar gas 0.03nmolC / L, air 0.06nmol / L. There was no significant difference in styrene levels between smokers and non-smokers. The upper limit of the 95% range is 5 nmol / L in blood, 0.07 nmol / L in alveolar gas and 0.15 nmol / L in air. The average exposure of workers to styrene was 2 μmol / L, and the concentration of styrene in the blood at the end of the shift was 12 μmol / L. The blood levels were significantly higher at 16 μmol / L on Thursday (11 μmol / L) than on Monday. There was also a similar difference in the morning blood samples (0.6 and 1.2 μmol / L, respectively). Morning and evening blood and air concentrations were significantly correlated. The next morning the blood concentration of contact was significantly higher than normal. Half of the blood reduction in 3.9 hours. Thus, the next morning the blood styrene as a biological monitoring indicators of occupational exposure to groups and individuals.