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目的动态监测新诊断2型糖尿病(T2DM)患者血糖水平、波动趋势以及与日常生活的关系。方法采取动态血糖监测系统(CGMS)对24例新诊断未经干预治疗的T2DM患者进行连续72 h的血糖监测,患者记录生活日记。结果 CGMS所测的血糖值与指端血糖值呈显著正相关(r=0.94,P(0.01)。患者一天中血糖较高的时间段为早餐后及中、晚餐后1～5 h,下午2点至凌晨1点是血糖高峰最集中(57.5%)的时间段,而75.5%的血糖低谷值出现在凌晨2点至5点。血糖(7.8 mmol/L及11.1 mmol/L所占的时间百分比分别为93%和57%。食物、运动、生活事件影响血糖波动。结论动态血糖监测能较详细地显示新诊断T2DM患者血糖水平波动的特征,食物、运动、生活事件是影响血糖波动的主要因素,为拟定更为合理的个体化治疗方案提供临床依据,为糖尿病教育提供更形象、更具说服力的材料。
Objective To dynamically monitor the blood glucose level, fluctuation trend and the relationship with daily life in newly diagnosed type 2 diabetes mellitus (T2DM) patients. Methods Twenty-four patients with newly diagnosed and untreated T2DM underwent a continuous glucose monitoring system (CGMS) for blood glucose monitoring for 72 hours. Patients recorded daily diaries. Results The blood glucose level measured by CGMS was significantly and positively correlated with the blood glucose level of the finger (r = 0.94, P <0.01). The high glucose level in the day was 1 ~ 5 h after breakfast and 1 ~ 5 h after dinner Point to 1:00 was the most concentrated period of peak blood glucose (57.5%), while 75.5% of the low blood glucose values occurred between 2 am and 5. Blood glucose (7.8 mmol / L and 11.1 mmol / L of the time percentage Respectively, 93% and 57% respectively.Food, exercise and life events affected the fluctuation of blood glucose.Conclusion Dynamic blood glucose monitoring can show the characteristics of blood glucose level in newly diagnosed T2DM patients in more detail.Food, exercise and life events are the main factors affecting blood glucose fluctuation , Providing a clinical basis for formulating a more rational individualized treatment plan and providing a more vivid and convincing material for diabetes education.