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目的探讨能反映＋ＧＺ负荷下动物全身血液动态转移规律的客观指标和方法。寻找可判断动物＋ＧＺ耐力的客观指标。方法对８条犬，用同位素亚锡喷替白蛋白（９９ｍＴｃ－ＤＴＰＡ－ＨＳＡ）标记其血液，用辐射测量仪从体外测得不同Ｇ负荷下由头至臀８个部位的血容动态变化曲线，用动态机能因子分析、药代动力学模型等数学方法分析、建模，进行参数估计。结果测得８个部位的血容动态变化曲线，其特点符合加速度生理；对其进行动态机能因子分析，得出符合犬的前半身及后半身血容总的变化规律的两个机能因子；对机能因子用二房室模型理论建模，提取出能反映动物Ｇ耐力和作用Ｇ值的特征参数Ａ、Ｂ、β、Ｖ和ＡＵＣ。结论本文提出的示踪测量技术和机能因子分析法，能客观的反映动物在不同Ｇ负荷作用下，动物全身血液动态转移的规律及动物耐力的变化。
Objective To explore objective indicators and methods that can reflect the dynamic changes of whole blood of animals under + GZ load. Looking for objective indicators that can judge animals + GZ endurance. Methods Eight dogs were labeled with isotope tin (99mTc-DTPA-HSA) and their blood samples were collected from 8 dogs with different G loads. Using dynamic factor analysis, pharmacokinetic model and other mathematical methods to analyze, modeling, parameter estimation. The results measured eight parts of the blood dynamic curve, which is consistent with the acceleration of physiology; its dynamic factor analysis, obtained in line with the first half of the dog’s body and the rear half of the total changes in blood volume of the two factors; The functional factor was modeled using a two-compartment model theory and characteristic parameters A, B, β, V and AUC reflecting the G values of endurance and function of animals were extracted. Conclusion The tracer technique and the method of factor analysis proposed in this paper can objectively reflect the changes of animal blood dynamics and animal endurance under different G loads.