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目的 探讨有创大动脉脉压(PP)水平与冠状动脉病变严重程度的关系。方法 对15 6例入选病例均行冠状动脉造影术。冠状动脉的严重程度用冠状动脉病变的血管支数及Gensini积分表示。所有病例均在术中测量主动脉血压。结果 高血压组较非高血压组冠心病患病率明显增高(73 .6 %vs 5 8. 5 % ,P =0 .0 32 )。高血压组患者冠状动脉三支血管病变的患病率(35. 2 %vs12 .3% )显著高于非高血压组(P =0 .0 0 1)。冠状动脉狭窄组,主动脉测压其收缩压(SBP)、PP均显著高于冠状动脉正常组,差异有统计学意义(P <0. 0 5 ) ,且SBP与PP随着狭窄支数的增加而逐渐增加。多因素分析结果显示,大动脉PP、年龄、高血压病史与冠心病冠状动脉狭窄程度的关系最为密切。结论 大动脉PP是冠心病冠状动脉狭窄发生发展的独立危险因素。
Objective To investigate the relationship between invasive arterial pressure (PP) and the severity of coronary artery disease. Methods A total of 15 6 selected patients underwent coronary angiography. The severity of coronary artery disease with coronary artery vessel count and Gensini points. Aortic blood pressure was measured intraoperatively in all cases. Results The prevalence of coronary heart disease was significantly higher in hypertension group than in non-hypertension group (73.6% vs 58.5%, P = 0.032). The prevalence of coronary tri-vessel disease in hypertension patients was significantly higher than that in non-hypertension patients (35.2% vs12.3%, P = 0.010). The systolic pressure (SBP) and PP in aortic stenosis group and aortic pressure measurement group were significantly higher than those in the normal coronary artery group (P <0.05), and the differences of SBP and PP with the number of stenosis Increase and gradually increase. Multivariate analysis showed that aortic PP, age, history of hypertension and coronary heart disease coronary stenosis degree most closely. Conclusion Aortic PP is an independent risk factor for coronary artery stenosis.