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吸烟对心血管疾病尤其对心肌梗塞和猝死是一个重要的危险因素。仅以美国而论,估计在565000名冠心病死亡者中30～40%是由于吸烟所致。尽管流行病学上有充分证明吸烟与心血管病有关,但吸烟如何形成这种危险,准确的机制还不清楚。一种假说认为吸烟通过内皮损害直接或间接地影响止血系统,使吸烟者容易患血管闭塞性疾患,如血栓形成性卒中和心
Smoking is an important risk factor for cardiovascular diseases, especially myocardial infarction and sudden death. In the United States alone, an estimated 30-40% of the 565,000 CHD deaths are due to smoking. Although epidemiologically there is sufficient evidence that smoking is linked to cardiovascular disease, the exact mechanism by which smoking is at risk is unclear. One hypothesis suggests that smoking directly or indirectly affects the hemostatic system through endothelial damage, making smokers susceptible to vascular occlusive disorders such as thrombotic stroke and heart