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血管紧张素Ⅱ受体及其拮抗剂的发现和研究，为抑制肾素—血管紧张素—醛固酮系统提供了一类新的药物。其代表药物ｌｏｓａｒｔａｎ较血管紧张素转换酶抑制剂（ＡＣＥＩ）具有更广泛的治疗作用，是继ＡＣＥＩ后又一新的突破，有可能替代ＡＣＥＩ。
The discovery and study of angiotensin II receptor and its antagonists provide a new class of drugs for inhibiting the renin-angiotensin-aldosterone system. Its representative drug losartan angiotensin-converting enzyme inhibitor (ACEI) has a broader therapeutic effect, is a new breakthrough after ACEI, may replace ACEI.