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目的研究妊娠中晚期心电图短P-R间期产生机制以及对胎儿的影响。方法对32例妊娠中晚期发现短P-R间期者(观察组)和30例P-R间期正常的中晚期孕妇(对照组)进行24h动态心电图(DCG)及胎儿心电图(FECG)检查;对观察组进行输氧一周后复查常规心电图(ECG)、FECG、及产后3个月复查ECG。结果观察组心率变异(HRV)较正常对照组明显降低,有显著性差异(P<0.001、P<0.005及P<0.01);观察组输氧后短P-R间期恢复正常,FECG前后变化不大。结论妊娠中晚期的P-R间期缩短与需氧量增加、自主神经功能失调、交感神经占优势相关,可作为中晚期妊娠者自主神经功能失衡的客观指标;对胎儿影响不大。
Objective To study the mechanism of short P-R interval electrocardiogram (ECG) and its effect on fetus during the second trimester of pregnancy. Methods Twenty-two cases of short-term PR in the second trimester of pregnancy (observation group) and 30 middle- and late-term pregnant women with normal PR interval (control group) were examined by 24-hour ambulatory electrocardiogram (DCG) and fetal electrocardiogram (FECG) After a week of oxygen for review of conventional electrocardiogram (ECG), FECG, and 3 months postpartum ECG review. Results The heart rate variability (HRV) of the observation group was significantly lower than that of the normal control group (P <0.001, P <0.005 and P <0.01). The short P-R interval returned to normal after the oxygen therapy in the observation group. Conclusions The shortening of P-R interval in middle and late pregnancy is associated with the increase of aerobic demand, dysfunction of autonomic nervous system and the prevalence of sympathetic nerves, which can be used as an objective indicator of imbalance of autonomic nervous function in middle and late pregnancy, with little effect on the fetus.