Evaluation of naproxen-induced oxidative stress,hepatotoxicity and in-vivo genotoxicity in male Wist

• 作 者: Mir Hilal Ahmad Mahino Fatima
• 机 构: SchoolofLifeSciences,InterdisciplinaryBrainResearchCentre
• 出 处: 药物分析学报:英文版
• 发表日期: 2018年6期
• 关键词: GENOTOXICITY NAPROXEN WISTAR rat ANTIOXIDANTS Oxidative stress DNA damage
• 基金项目: supported by grants from DBT NER(BT/PR16164/NER/95/88/2015),DST PURSE-(Phase-II)(PAC-JNU-DSTPURSE-462),UGC RNW,UGC SAP at the level of DRS-I&II,and UPE-II,JNU(Project Id No.247)

Naproxen (NP), a nonsteroidal anti-inflammatory drug (NSAID), is used for the treatment of common pain, inflammation and tissue damage. Genotoxicity testing of NP is of prime importance as it represents the largest group of drugs to which humans are expos