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目的:探讨盐酸丙帕他莫复合异丙酚在无痛人工流产术中的应用效果。方法:回顾性分析2013年12月至2015年12月东莞市麻涌镇医院行无痛人工流产术的130例产妇的临床资料,随机数表法分为两组。对照组仅应用异丙酚治疗,观察组采用盐酸丙帕他莫复合异丙酚治疗,比较两组产妇的临床疗效。结果:观察组、对照组的总有效率分别为98.46%、89.23%,两组相比,差异具有统计学意义(P<0.05);观察组T1的视觉模拟量表(VAS)评分为(15.57±3.26)分,T2(16.91±4.18)分,T3(19.33±4.65)分,T4(21.85±5.17)分,T5(22.96±5.58)分,均明显低于对照组T1的VAS评分为(27.13±9.05)分,T2(31.62±8.62)分,T3(40.25±9.48)分,T4(51.03±10.28)分,T5(56.75±10.34),差异具有统计学意义(P<0.05);观察组的体动评分(0.41±0.18)分,麻醉起效时间(3.04±0.61)min,苏醒时间(6.95±1.66)min,异丙酚用量(141.06±31.72)mg,均少于对照组体动评分(2.05±0.93)分,麻醉起效时间(5.58±1.27)min,苏醒时间(10.04±1.93)min,异丙酚用量(179.35±42.87)mg,差异具有统计学意义(P<0.05);对照组的手术时间(8.02±4.18)min观察组的手术时间(7.45±2.63)min,组间比较,差异无统计学意义(P>0.05)。结论:盐酸丙帕他莫复合异丙酚在无痛人工流产术的应用效果显著。
Objective: To investigate the effect of propranolol hydrochloride combined with propofol in painless artificial abortion. Methods: The clinical data of 130 cases of painless abortion in Mayong Town Hospital of Dongguan City from December 2013 to December 2015 were retrospectively analyzed. The random number table was divided into two groups. The control group was treated with propofol only. The observation group was treated with propamtol hydrochloride combined with propofol. The clinical efficacy of the two groups was compared. Results: The total effective rates of the observation group and the control group were 98.46% and 89.23% respectively, there was significant difference between the two groups (P <0.05). The visual analog scale (VAS) score of the observation group was (15.57 ± 3.26), T2 (16.91 ± 4.18), T3 (19.33 ± 4.65), T4 (21.85 ± 5.17) and T5 (22.96 ± 5.58) respectively, which were significantly lower than those of the control group (27.13 (P <0.05). The difference was statistically significant (P <0.05). The difference between the two groups was statistically significant (P <0.05) Body movement (0.41 ± 0.18), duration of onset of anesthesia (3.04 ± 0.61) min, recovery time (6.95 ± 1.66) min and dosage of propofol (141.06 ± 31.72) mg were lower than those of the control group 2.05 ± 0.93), the onset time of anesthesia was (5.58 ± 1.27) min, the recovery time was (10.04 ± 1.93) min, the dosage of propofol was (179.35 ± 42.87) mg, the difference was statistically significant (P <0.05) The operation time (8.02 ± 4.18) min in the observation group was 7.45 ± 2.63 min. There was no significant difference between the two groups (P> 0.05). Conclusion: The effect of propafenone hydrochloride combined with propofol in painless artificial abortion is remarkable.