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目的:比较介入治疗与介入联合放疗治疗胰腺癌的临床效果。方法:我院住院治疗,并且无法手术的胰腺癌患者68例,随机分为观察组和对照组各34例。观察组患者均给予介入联合放疗治疗,对照组患者仅给予介入治疗。比较2组患者的中位生存期(MST)和总生存率(OS)。结果:观察组34例患者的MST为12.1个月,1年OS为47.06%,2年OS为32.35%。对照组34例患者的MST为7.5个月,1年OS为20.59%,2年OS为5.88%。观察组患者的MST明显长于对照组患者(P<0.05);1年OS和2年OS均明显高于对照组患者(P<0.05)。结论:对于无法手术治疗的胰腺癌患者,使用介入联合放疗可以取得更好的治疗效果,值得临床推广。
Objective: To compare the clinical effects of interventional therapy and interventional radiotherapy in the treatment of pancreatic cancer. Methods: 68 hospitalized patients with inoperable pancreatic cancer were randomly divided into observation group (34 cases) and control group (34 cases). Patients in the observation group were given interventional radiotherapy, while those in the control group were given only interventional therapy. The median survival (MST) and overall survival (OS) were compared between the two groups. Results: The MST of 34 patients in observation group was 12.1 months, the one-year OS was 47.06% and the two-year OS was 32.35%. In the control group, 34 patients had a MST of 7.5 months, a one-year OS of 20.59% and a 2-year OS of 5.88%. The MST in the observation group was significantly longer than that in the control group (P <0.05). The 1-year OS and 2-year OS were significantly higher than those in the control group (P <0.05). Conclusion: For patients with pancreatic cancer who can not be surgically treated, interventional radiotherapy can achieve better therapeutic effect and is worthy of clinical promotion.