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患者男性,41岁,日本人。因短期咽痛后出现高热、面,颈部痛性红色斑块伴口疮入院。颈部皮损活检显示真皮乳头明显水肿,伴弥漫致密的嗜中性白细胞和淋巴细胞浸润,无明显白细胞碎裂性血管炎表现。实验室检查:白细胞计数13.2×10~9/L,中性白细胞0.74;血沉36mm/h;C-反应蛋白阳性;血清铜28.2μmol/L 及 IgD2.52mg/L,并作了 HLA 研究。扁桃体和血培养均阴性。根据临床及组织学表现诊断为 Sweet 综合征(SS)。经服用强的松龙30mg/d 后症状消失,但停药后又复发。每4～5个月复发一次。有时发作的同时伴有
Male patient, 41 years old, Japanese. Due to short-term sore throat after fever, noodles, neck painful red plaque with aphthous hospital. Neck lesion biopsy showed dermal papillary edema, with diffuse dense neutrophil and lymphocyte infiltration, no obvious manifestations of leukocytic fragaria. Laboratory tests: white blood cell count 13.2 × 10 ~ 9 / L, neutrophils 0.74; erythrocyte sedimentation rate 36mm / h; C-reactive protein positive; serum copper 28.2μmol / L and IgD2.52mg / L, and HLA research. Tonsils and blood cultures were negative. Sweet syndrome (SS) was diagnosed on the basis of clinical and histological findings. After taking prednisolone 30mg / d symptoms disappear, but relapse after stopping. Every 4 to 5 months recurrence. Sometimes accompanied by attacks at the same time