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纵观卒中记载,2%～7%年轻脑梗塞患者系血液学原因造成,其中纤溶系统变化结果不一,更多检测到的是后天所致血栓前状态的抗磷脂抗体和狼疮抗凝因子(LA)。本文旨在评估中青年卒中患者出现 LA 和纤溶系统的异常情况。选连续发病的中青年缺血性卒中患者33例(男27例,女6例),年龄<50岁(23～49岁)。诊断为经 CT 确定的脑梗塞和急性神经缺失症状持续24h 以上者。在其发病后对 LA、抗心肌磷脂质抗体(aCL)循环效价,以及凝血和纤溶系统进行至少三个月以上的检测。检测前二周停用一切影响凝血,纤溶系统和血小板功能的药物。LA 由四个不同凝血试验来确定:活化部分凝
Throughout the stroke record, 2% to 7% of young patients with cerebral infarction caused by hematological causes, including changes in fibrinolytic system results vary, more detection is acquired acquired prothrombotic antiphospholipid antibodies and lupus anticoagulant factor (LA). This article aims to assess the appearance of LA and fibrinolytic system abnormalities in young and middle-aged stroke patients. Thirty-three middle-aged and young patients with ischemic stroke were selected (27 males and 6 females), aged <50 years (23-49 years). Diagnosis of CT-confirmed cerebral infarction and acute neurological deficits persisted for more than 24h. LA, anti-cardiolipin antibodies (aCL) circulating titers, and coagulation and fibrinolysis systems were tested for at least three months after their onset. Two weeks before the test disable all affect coagulation, fibrinolytic system and platelet function of the drug. LA is determined by four different coagulation tests: activated partial coagulation