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5—FU磁性微球载体的设计,旨在口服后在体外应用磁场,使其吸着在食道的癌变区,释放出5—FU,被癌组织吸收,用以治疗食道癌。这样可以用较小的剂量在靶区产生较高的浓度,而身体的其他正常组织药物浓度就相应的降低,因此使装物的毒副作用降低,并加速和加强产生药效。此外强磁场也具有抑癌作用。5—FU是临床常用的抗癌药物,对胃癌等多种癌症疗效显著,但它和其他抗癌药一样,在抑制和杀灭癌细胞的同时,也危害正常细胞和组织,特别是生长旺盛的消化道粘
5-FU magnetic microsphere carrier designed to be applied in vitro after oral magnetic field, making it inhalation of esophageal cancerous areas, the release of 5-FU, was absorbed by the cancer tissue for the treatment of esophageal cancer. This allows the use of smaller doses to produce a higher concentration in the target area, while the body’s other normal tissue drug concentration is reduced accordingly, thus reducing the toxic side effects and accelerating and enhancing efficacy. In addition, strong magnetic field also has tumor suppressor effect. 5-FU, a commonly used anticancer drug in clinical practice, has a significant effect on various cancers such as gastric cancer. However, 5-FU, like other anticancer drugs, inhibits and kills cancer cells as well as normal cells and tissues, Gastrointestinal sticky