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疼痛是颞下颌关节功能紊乱综合征(TMJDs)的常见症状,保守治疗对缓解疼痛和功能紊乱常常有帮助。对于那些不能手术而采用保守治疗效果不佳者作者进行了关节腔内注射过氧化物歧化酶(SOD)的初步试验。过氧化物是组织炎症与损伤的一种重要介质,能直接损伤组织细胞使滑液及胶原变性,溶解透明质酸,灭活抗蛋白酶,将花生四烯酸转变为有活性的产物,进一步使关节组织损伤而出现临床症状。SOD是一种能局部使用的新的抗炎物质,属于长效非类固醇混合物,其
Pain is a common symptom of temporomandibular joint dysfunction syndrome (TMJDs), and conservative treatment is often helpful to relieve pain and dysfunction. A preliminary trial of intra-articular injection of superoxide dismutase (SOD) was performed for those inoperable who underwent conservative treatment. Peroxides are an important mediator of tissue inflammation and injury. They can directly damage tissue cells to degenerate synovial fluid and collagen, dissolve hyaluronic acid, inactivate anti-protease, and convert arachidonic acid into an active product. Further, Joint tissue injury and clinical symptoms. SOD is a new anti-inflammatory material that can be used topically and belongs to the long-acting non-steroidal mixture, which