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目的: 观察过敏性鼻炎合并支气管哮喘患者中西药物或手术( 鼻翼管神经电灼术) 治疗的远期临床疗效。方法: 30 例患者中, 手术组19 例、非手术组11 例。10 a 前后, 均使用日本FUDAC60 型肺功能仪和ASTOGRAGHTCK6100 H 型气道反应仪, 在缓解期上午测定肺功能和气道反应性。结果: 2 组临床表现均好转, 手术组更明显。2 组10 a 前后肺功能、气道反应性自身对比: 用力肺活量均增高、25 % 用力肺活量呼气流速与身高之比均降低( P< 0-05) 。Rrs ( 呼吸阻力) 、Dmin ( 药物累计量) 增高, SGrs ( 诱导控制值下降斜率) 明显降低。组间对比: 非手术组各项肺功能指标均比手术组有大幅度改善。非手术组Rrs 增高小于手术组, Dmin 增高大于手术组, SGrs 降低小于手术组。结论: 两种治疗均使患者临床症状、肺功能和气道反应性有不同程度改善。非手术组肺功能和气道反应性的指标较手术组改善更大
Objective: To observe the long-term clinical efficacy of Chinese and Western medicine or surgery for the treatment of allergic rhinitis with bronchial asthma. Methods: Among the 30 patients, 19 patients in the operation group and 11 patients in the non-operation group. 10 a before and after, were used Japan FUDAC 60 pulmonary function meter and ASTOGRAGH TCK 6100 H-type airway response, determination of pulmonary function and airway reactivity in the morning of remission. Results: The clinical manifestations in both groups improved and the operation group was more obvious. The pulmonary function and airway responsiveness in both groups before and after 10 years of treatment were compared with those of forced vital capacity, and the ratio of expiratory flow rate to height was decreased at 25% forced vital capacity (P <0-05). Rrs (respiratory resistance), Dmin (drug cumulative amount) increased, SGrs (induced control value decreased slope) decreased significantly. Comparison between groups: non-surgical group of lung function indicators were significantly improved than the surgery group. The increase of Rrs in non-operation group was smaller than that in operation group, Dmin increased more than that in operation group, SGrs decreased less than operation group. CONCLUSIONS: Both treatments improved clinical symptoms, lung function, and airway responsiveness to varying degrees. The indexes of lung function and airway reactivity in non-operation group improved more than those in operation group