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关于乙醇对孕胎细胞遗传学的影响,进行了动物模型的实验研究。采用出生后10～40周的成熟雌鼠,在妊娠前四周和妊娠期间投以0%、10%、20%、40%的乙醇与固体饲料一同使鼠自由摄取,然后测定其摄入量。观察到交尾栓后作为妊娠0.5日,妊娠10.5日后开腹探查,取得胎仔,用直接法制作染色体标本,双肓法进行分析。投与乙醇4周后的雌鼠的体重,40%组明显减少。对于胎仔的影响,从0%～20%各组的着床
Regarding the effect of ethanol on gestational cytogenetics, experimental studies in animal models were conducted. Mature females aged 10 to 40 weeks after birth were challenged with 0%, 10%, 20%, 40% ethanol and solid feed for the first four weeks of gestation and during pregnancy to determine their intakes. Opposite plug observed as 0.5 days after pregnancy, pregnancy 10.5 days after laparotomy to obtain fetuses, direct method of making chromosomal specimens, double-fold method for analysis. After 4 weeks of administration of ethanol, the body weight of the female rats was significantly reduced by 40%. The impact on the fetus, from 0% to 20% of the implantation of each group