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关于乙肝疫苗接种后的免疫期限仍有一些疑问尚未解决。某些资料提出,抗HBs 水平依赖于最后一次加强剂量后抗HBs 所能达到的峰值,而且对乙肝感染的保护性与抗HBs 水平的持久性是平行的,如果抗HBs 水平高,则保护性持续时间长。作者采用Merck 血源性疫苗(20μg),对象为HBsAg、抗HBg,抗HBc 均阴性的健康青年。观察组男性12名、女性5名,平均年龄为24.6±3.3,对照组男性10名、女性6名,平均年龄24.4±3.0;观察组于0、1、12月各注射20μg,对照组于0、1、6月注射同样剂量;在首次注射后2、6、7、13、
There are still some questions about the duration of the immunization after hepatitis B vaccination has not been resolved. Some data suggest that anti-HBs levels depend on the peak anti-HBs achieved after the last booster dose and that protection against hepatitis B infection is parallel to the persistence of anti-HBs levels and that if anti-HBs levels are high, protective Long duration. The authors used Merck blood-borne vaccine (20 μg) for healthy young women who were negative for HBsAg, anti-HBg, and anti-HBc. The observation group consisted of 12 males and 5 females, with an average age of 24.6 ± 3.3. The control group consisted of 10 males and 6 females, with an average age of 24.4 ± 3.0. In the observation group, 20 μg each were injected in 0, 1 and 12 months, , The same dose in January and June; after the first injection 2,6,7,13,