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42例急性心肌梗塞(AMI)患者,在胸痛开始后平均2.3±1.2小时(22分钟～6小时)给予重组组织纤维蛋白溶酶原激活剂(rt-PA)。患者先静注肝素40U/kg,然后静注rt-RA10mg,继以滴注rt-PA第1小时90mg,第2小时50mg,共150mg。并维持肝素滴注每小时10～12U/kg,使部分凝血激酶时间保持在60～80秒钟。
Forty-two patients with acute myocardial infarction (AMI) received an average of 2.3 ± 1.2 hours (22 minutes to 6 hours) of recombinant tissue plasminogen activator (rt-PA) after the onset of chest pain. Patients first intravenous injection of heparin 40U / kg, then intravenous rt-RA10mg, followed by infusion of rt-PA first hour 90mg, the first two hours 50mg, a total of 150mg. And maintain heparin infusion per hour 10 ~ 12U / kg, so that partial thromboplastin time to maintain in 60 to 80 seconds.