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选择工龄在１０ 年以上、年龄在４５ 岁以下的７６ 名ＣＳ２ 作业工人作为接触组；在同一工厂棉浆车间内选择相同年龄和工龄范围、曾经接触过ＣＳ２ 但现在已停止ＣＳ２ 接触５ 年以上的３３ 名工人作为干预组；从未接触过ＣＳ２ 的２３ 名工人作为对照组。对以上对象进行了流行病学横断面调查表明，接触组ＳＳｅ 含量高于对照组（Ｐ＝ ０．０００１）。用多元逐步回归分析控制了一些混杂因素后进一步显示，ＳＳｅ 的含量与ＣＳ２ 接触有一定的关系（偏相关系数为－ ０．２８１４），且ＣＳ２ 对ＳＳｅ 含量起负贡献（偏回归系数β为－ １５．５０９８），提示低浓度ＣＳ２ 接触可能是ＳＳｅ 含量降低的独立危险因素；干预组ＳＳｅ 含量高于对照组（Ｐ＝ ０．００８），提示低浓度ＣＳ２ 接触引起ＳＳｅ含量的改变可能是不可逆的
Sixty-two CS2 workers aged over 10 years and under the age of 45 were selected as the contact group. CS2 was selected for the same age and seniority in the cotton mill in the same factory but has been discontinued for more than 5 years Thirty-three workers served as an intervention group and 23 workers who had never been exposed to CS2 served as controls. The epidemiological cross-sectional survey of the above subjects showed that the content of SSe in the contact group was higher than that in the control group (P = 0.0001). Multiple stepwise regression analysis controlled some confounding factors and further showed that the content of SSe has a certain relationship with CS2 exposure (partial correlation coefficient is -0.2814), and CS2 negatively contributes to SSe content (partial regression coefficient β is - 15.5098), suggesting that exposure to low concentrations of CS2 may be an independent risk factor for the decrease of SSe content. The SSe content in the intervention group is higher than that in the control group (P = 0.008), suggesting that changes in the SSe content caused by low concentrations of CS2 may be irreversible